The NITC Inhalation Exposure System is manufactured by Korean company HCT. Very few information about toxicity is known to public and no formal studies. Requirement for toxicity studies are: Monitoring particle concentration, size and size distribution chamber.

Feaures.

• Nose-only exposure chamber system.
• Inhalation toxicity of drug, pesticides and chemicals.
• Multifunctional system can be available depending upon purpose, particles and laboratory animals.
• Nanoparticles generation/monitoring system (ISO 10801, 10808).
• Automatic generation/monitoring system.
• Systems comply with GLP, REACH, GHS and OECD guidelines.

Working Principle.

Specifications.

Particle Generation System:

• Particle size: 1nm - 100µm.
• Particle concentration:0–1012#/cm3(<300 mg/cm3)
• Particle type:NaCL, KCl, Au, Pb, Mn, SiO₂, TiO₂, Fe₂O₃, Soot, CNT, Powder.
• Enable to generate monodisperse or polydisperse aerosol
  • Standard deviation of generated particle: > 1.05
• Aerosol cyclone: 5 µm cut-off.
• Adapted to ISO 10801.

Nose-only Exposure Chamber:

• Top-down flow type chamber.
• Dimension
  • 1000 x 1000 x 2000 mm
• Material: SUS 316
• Inside Illumination: 200 Lux.
• Port number of chamber: 36ea (6 x 6).
• Sampling flow-rate per port: 1L/min.
• Dynamic air flow: 12 – 15 air changes per hour.
• Adapted to OECD guideline (TG-403, 412 and 413).

See more specifications on the equipment brochure.

Control & Monitoring Program.

• Environmental monitoring: Temperature, Humidity, Differential pressure, Air flow-meter, O2
• Concentration and particle size distribution.
• The state of exposure conditions.
• Inter-lock monitoring, water flushing monitoring and etc.
• Particle generation, dilution ratio and flowrate control.
• Mass flow controller.
• Make-up air valve and exposure air valve control.
• Adapted to FDA and OECD guideline.