The WITC Inhalation Exposure System is manufactured by Korean company HCT. Very few information about toxicity is known to public and no formal studies. Requirement for toxicity studies are: Monitoring particle concentration, size and size distribution chamber.

Features.

• Inhalation toxicity of drug, pesticides and chemicals.
• Multifunctional system can be available depending upon purpose, particles and laboratory animals.
• Nanoparticles generation/monitoring system (ISO 10801, 10808).
• Automatic waste control/monitoring system.
• Automatic washer.
• Systems comply with GLP, REACH, GHS and OECD guidelines.
• Patent test substance dispenser system.

Working Principle.

Specifications.

Particle Generation System:

• Particle size: 1nm - 100µm.
• Particle concentration: 0 – 1012 #/cm3 (<300 mg/cm3)
• Particle type: NaCL, KCl, Au, Pb, Mn, SiO₂, TiO₂, Fe₂O₃, Soot, CNT, Powder, etc,
• Enable to generate monodisperse or polydisperse aerosol
• Aerosol cyclone: 5 µm cut-off.
• Adapted to ISO 10801.

Inhalation Whole Body Chamber:

• Top-down flow type chamber.
• Dimension
  • WITC-07 model: 800 x 800 x 2150 mm (0.7 m3).
  • WITC-15 model: 1300 x 1000 x 2150 mm (1.5 m3).
• Clean Level: Class 1.000
• Material: SUS 316 – 2.0T.
• Inside Illumination: 200 Lux.
• Observation Windows: U.V. Filtering, 4 windows.
• Adapted to OECD guideline (TG-403, 412 and 413).

Control & Monitoring Program.

• Environmental monitoring: Temperature, Humidity, Differential pressure, Air flow-meter, O2.
• Concentration and particle size distribution.
• The state of exposure conditions.
• Inter-lock monitoring, water flushing monitoring and etc.
• Particle generation, dilution ratio and flowrate control.
• Mass flow controller.
• Make-up air valve and exposure air valve control.